How do we make the best decision to accept a pediatric donor heart?

How do we best treat patients with ischemic heart disease?

Despite investigations over several decades, it is still difficult to define an optimal treatment strategy for patients with ischemic heart disease. Some of the many reasons for this dilemma include delayed and highly variable symptomatic presentation, lack of a clear relationship between symptom severity and outcome, a changing population (aging and more women), changing therapies, and a relat...

How do we make Scholarship Semantic?

I am grateful for the opportunity to comment on the opportunities and challenges of using semantic approaches in scholarly publishing. (“Scholarship” covers many fields of endeavour and should extend beyond the ivory tower of academia.) We were asked to provide crazy ideas and a polemic, where arguments are backed by personal conviction as much as proven experience. The primary aim of a polemic...

Pollution and respiratory morbidity: how much do we accept?

What Do We Know, How Do We Know It, and How Can We Best Apply It?

Adequate Nutrition May get You Home: Effect of Caloric/Protein Deficits on the Discharge Destination of Critically Ill Surgical Patients 37 D. Dante Yeh, MD; Eva Fuentes, MD; Sadeq A. Quraishi, MD, MHA, MMScH; Catrina Cropano, MSc; Haytham Kaafarani, MD, MPH; Jarone Lee, MD, MPH; David R. King, MD; Marc DeMoya, MD; Peter Fagenholz, MD; Kathryn Butler, MD; Yuchiao Chang, PhD; and George Velmahos...

How do we choose the best donor for T-cell-replete, HLA-haploidentical transplantation?

In haploidentical stem cell transplantations (haplo-SCT), nearly all patients have more than one donor. A key issue in the haplo-SCT setting is the search for the best donor, because donor selection can significantly impact the incidences of acute and chronic graft-versus-host disease, transplant-related mortality, and relapse, in addition to overall survival. In this review, we focused on fact...